Endocrine Abstracts

Introduction: Widespread use of abdominal imaging has led to the identification of an increasing number of adrenal incidentalomas (AI) in the last decades. Causes of these adrenal masses are multiple.Aim: The aim of this study was to investigate the clinical and hormonal characteristics of AI.Materials and methods: The study was a retrospective monocentric analysis of 44 patients with AI who underwent radiographic and endocrine eva...

Introduction: Cardiothyreosis (CT) is the most frequent and dangerous complication of hyperthyroidism (HT). It is defined as an association of HT with severe heart abnormalities such as: rhythmic troubles, heart and/or coronary insufficiency. The aim of our study was to describe the frequency and the clinical characteristics of CT in Graves’ disease (GD).Methods: Patients with GD were enrolled into a retrospective study. The prevalence and the clini...

Introduction: Graves’ ophthalmopathy (GO) is an autoimmune disorder affecting the retro-orbital tissues. It represents the main extra- thyroidal expression of Graves’ disease (GD). Its onset and progression are influenced by several factors that are potentially modifiable. The aim of this study was to identify risk factors for severe GO.Methods: Patients with GD were enrolled into a retrospective study. We compared possible risk factors and var...

Introduction: Hemochromatosis is a disorder caused by an excess of iron deposition in the parenchymal cells that leads to organ dysfunction. In patients with secondary hemochromatosis due to multiple blood transfusions, endocrinopathies such as diabetes mellitus, hypopituitarism frequently develop.Herein we report the case of a patient with B-thalassemia major who developed diabetes mellitus, hypopituitarism and primary hypoparathyroidism due to secondar...

Introduction: Mixed gonadal dysgenesis with 45X/46XY mosaicism is considered to be a rare disorder of sex development. This condition is characterized by a phenotypically very heterogeneous clinical presentation. In fact, the individuals with 45X/46XY mosaicism ranged from phenotypically normal men with azoospermia, going through individuals with genital ambiguity, to women with Turner syndrome.Herein, we describe a phenotypically Turner-like female with...

Introduction: Simultaneous occurrence of acute pancreatitis and diabetic ketoacidosis represents a very rare complication of antipsychotic medications.Herein we report the case of acute pancreatitis and diabetic ketoacidosis in a non-diabetic patient while on treatment with haloperidol, chlorpromazine and carbamazepineCase report: Mr. Z A is a 50-year-old non-diabetic man who was diagnosed with psychotic disorder and treated with h...

Introduction: Riedel thyroiditis is a rare form of infiltrative and fibrotic disease of the thyroid which may involve neighbouring tissues. The main differential diagnosis of Riedel thyroiditis includes malignant tumors and fibrosing Hashimoto’s thyroiditis.Herein, we report a case of concurrent Riedel’s disease and Hashimoto’s thyroiditis.Observation: A 45-year-old woman was diagnosed with goiter and hypothyroidism....

Introduction: Renal complications in Graves’ disease are rare and may be related either to the disease itself or secondary to antithyroid drugs.Methods: We report seven cases of renal damage in patients with Graves’ disease treated with Benzylthiouracyl collected over a period of 14 years.Results: There were seven women with a mean age of 37.86±14.25 years (19–61 years).Six patients develo...

Introduction: Systemic amyloidosis leads to functional compromise of various organs through infiltration of these tissues by amyloid protein.The aim of this study was to determine the endocrine disorders in patients with systemic amyloidosis.Methods: During the period from 1975 to 2006, we collected 580 patients with renal amyloidosis confirmed by histological exam. We selected 123 patients with hormonal exploration. 55 patients ha...

Introduction: Thyroid gland may be asymptomatically involved in most patients with secondary systemic amyloidosis. However, clinically detectable amyloid goiter is quite rare; often it is seen in patient with kidney involvement. We report one case of amyloid goitre without kidney manifestation.Case report: A 30-year-old male diagnosed with bilateral bronchiectasis since 1992 was admitted with rapidly growing goiter associated with dysphagia for solids, c...